Discover Combinations

Efficiently solving large & complex search spaces to support drug-dose combination discovery

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What is done today:

Combination validation

Inputs:
lead target, pick a dose, and combine with SOC
Biological Models

In-Vitro

In-Vivo

Ex-Vivo

Outputs:
LIMITED SEARCH SPACE & VALIDATION

1-8 different combinations tested

KYAN’s APPROACH:

Combination Discovery

Inputs:
12 drugs at three different dose ranges
Biological Models

In-Vitro

In-Vivo

Ex-Vivo

Outputs:
LARGE SEARCH SPACE & DISCOVERY

Over 500k possible combinations with dose/effect relation