Publications

A Case Report on Functional Precision Medicine Guiding Treatment in Refractory Leiomyosarcoma

ROICAM Indonesia 2025
Soft Tissue Sarcoma

Background

The management of metastatic soft tissue sarcoma presents a significant clinical challenge once the disease progresses beyond standard first- and second-line therapies due to treatment resistance. Innovative strategies that move beyond a one-size-fits-all approach and towards personalized medicine could support in overcoming this resistance. Functional Precision Medicine (FPM), which assesses the response of a patient’s living cancer cells to various drugs, represents a novel approach to guide therapy in such refractory cases.

In this poster we present the case of a 65-year-old female with an initial diagnosis of Solitary Fibrous Tumor which later developed into Leiomyosarcoma. This poster describes how this patient was able to achieve a significant partial response after treatment with an Optim.AI™-guided therapy.

 

Authors:  Cosphiadi Irawan¹, Agi Satria Putranto² , Ardhi Rahman Ahani¹

1. Div of Hematology Med Oncology, Dept of Internal Med, FKUI – RSCM, Jakarta, DKI Jakarta, Indonesia

2. Div of Digestive Oncology, Dept of Surgery, FKUI – RSCM, Jakarta, DKI Jakarta, Indonesia

 

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